By Dr. Yuhong Dong
Editor’s Note: This second installment in a multi-part series about the human papillomavirus, or HPV, vaccine examines studies that link the vaccines to increased risk of serious neurological and autoimmune disorders. Read Part 1 here.
Summary of key facts
- A Danish review of 79,102 female and 16,568 male subjects, found human papillomavirus (HPV) vaccines had significantly increased rates of serious nervous system disorders. Postural orthostatic tachycardia syndrome (POTS) and complex regional pain syndrome were judged “definitely associated” with the HPV vaccine.
- A large Danish and Swedish study including nearly 300,000 girls found a significant association between the HPV vaccine and increased rates of Bechet’s syndrome (rate ratio 3.37), Raynaud’s disease (1.67) and type 1 diabetes (1.29).
- A large study including 3 million Danish and Swedish women aged 18 to 44, identified seven adverse events with statistically significant increased risks following HPV vaccination: Hashimoto’s thyroiditis, celiac disease, lupus erythematosus, pemphigus vulgaris, Addison’s disease, Raynaud’s disease and encephalitis, myelitis, or encephalomyelitis.
- A 2017 French study of over 2.2 million young girls found evidence of a 3.78-fold increased risk of Guillain-Barré syndrome (GBS). A 2011 U.S. study found nearly a two-and-a-half to 10 times greater risk of acquiring GBS within six weeks post-Gardasil vaccination.
- While the underlying mechanisms causing these autoimmune reactions are not yet fully understood, some researchers speculate that the sizable overlap in protein sequences between the HPV and the human genome may cause the immune system to attack itself. Others are concerned that the adjuvants (such as aluminum) used to attract the attention of the immune system may be causing harm.
Neurological and autoimmune disorders
Danish review found increased nervous system disorder
In 2020, a group of Danish scientists conducted a systematic review of the overall benefits and harms of HPV vaccines….