So this came to the attention of the inner worlds today. It is not new, but it is fresh! Just like those eggs those gorgeous chickens lay that we fry, poach and scramble. The article is entitled: “Chicken Egg Yolk Antibodies (IgYs) block the binding of multiple SARS-CoV-2 spike protein variants to human ACE2” and it was published by a Chinese group in January 2021.
These IgY antibodies are amazing little guys! They don’t activate complement, they don’t activate rheumatoid factors in humans and so don’t aggravate the inflammatory responses! What they do do? They neutralize many pathogens including RSV (remember this when they push that new MRNA shot on you against RSV) including SARS-CoV-2 which has been shown both in vitro and in vivo.
IgY antibodies are found in birds, reptiles and lungfish, but especially in chicken egg yolks! How cool is that, eh? It’s basically the functional equivalent to human IgG.
Right to the bottom line we go!
In summary, the anti-Spike-S1 IgYs showed significant neutralizing potency against SARS-CoV-2 pseudovirus, various S mutants, and even SARS-CoV in vitro.
And no conflicts of interest. I read the methods and they are as sound as any methodology. They checked multiple viruses, variations of the S protein competitive inhibition of ACE-2 binding and found that IgY competed real well for binding sites showing significant neutralizing (SARS pseudoviruses, anyway) ability….